The 800 motor being the same as the 440, 600 , and 700 small block has small ports in it so its not going to flow the airflow needed for the big bore. The old big block 800 has larger ports.
I was looking at this motor when it came out and if there was a benefit of a big bore I would have done it.
All I do is porting (cylinder and case), a billit head, and pipe kit.
Turbos will loose at altitude as well, but just turn up the boost and your back to square one.