I ride a KTM 500 with a self-designed turbo kit.
It works very well and I'm very happy with it.
Have not tested a 450 turbo but feel that the 500 has high torque and it starts boosting early. Full turbo pressure already at about 6000 rpm.
There are of course different solutions to build a turbo kit. Good and bad designs.
Therefore, you should probably be careful to judge out all the turbo builds.
KMS seems to do everything thoroughly and cut no corners to build a turbo kit that provides good driveability and reliability. There are more questions in Boondockers design and looks to be a simpler and cheaper construction.
Reliability-wise the 500 engine manages turbo very good if you do not boost too much, running with good fuel and avoid overreving. (Boosting 10 psi, 102 octane race fuel and a 10:1 low comp piston)
Have today ridden almost 100 hours on it without rebuilding it. (The bike was brand new when i installed the turbo)
Another advantage is that the 500 has a plain bearing crankshaft. It works with higher oil pressure and can handle higher loads than a roller bearing crankshaft.
Because it is so powerful you do not strain the engine unnecessarily, and with relatively low revs.
It is written much about the downside of wide-ratio tranny but I feel it very suitable for the turbo bikes. It revs up so quickly that a cloe ratio tranny results that you more or less hit the revlimiter all the time.
Here you can read more about my turbo build:
http://www.snowest.com/forum/showthread.php?t=325741