Ive always heard that 100ll wasnt the best for high rpm more than any other negative about it.
Ive never ran it but going to start working with it this winter, theres to many turbo sleds running it over the years that I can lean towards the side of "best fuel for the money"
Ive always ran 110 sunoco and it has always been consistent and readily available for me but the price has almost doubled (which I dont mind paying if its what works)
I can get 100ll as easily as sunoco/VP and at less than half the price im definitely going to try some. With the whole RPM thing running it in a boosted apex (over 10K rpm) was always my concern.
Theres also some places close to me advertising ethanol free 93 but its over $6.00 per gallon! over $10 for sunoco (used to pay $6.50) and $4.20 for 100ll. With crappy pump fuel getting in the mid 3.00's Im ready to start running av gas!
I usually run low boost 12 psi 5-7K feet with a head shim 9.3:1 which has proven to me to be safe with 100% pump fuel but no DET sensor I usually put in about 2 gallons of 110 for some peace of mind. I can attest that when I run 17-18 psi with straight 110 when the sled is cold it definitely starts slightly harder and has slightly less on off throttle response until boost is built.
I wouldn't think or take concern to it about a higher rpm engine. It's a fuel that's ignited by spark. I had an apex with the head shim, When I first got it I had run av gas through it with pump gas mixed in, then I ran out of av and just ran the pump gas, I can get 94 so it worked fine, Ran it at 18# some days and never seen a det code or had an issue.