Baffles would be a great way to go. The only other concern is the weight. I don't know for sure but gas weighs around 6-7 lbs per gallon (high side to be safe), thats around 500 lbs in gas plus the weight of the tank, thats a lot of tounge weight. Will your tounge jack handle the weight?
It can be done but pay attention to how you load your trailer, you'll want to load sleds and gear toward the back to help compinsate, depending on how much fuel is in the tank, each time will be a little different. Another thing to consider is your trailer frame in that area, is it heavy duty enough, not just short term but think a few years down the road, Ive modded my trailers quite a bit and learned to "over build".
As for your truck, good choice, I also have a f350. If you don't have air bags on the rear, get some. I have the FIRESTONE.
Lastly, your hitch, spend a little extra $ and get a solid hitch. My trucks have a UNI-MOUNT, it's adjustable, has 2" and 2 5/16" ball and is rated at 14,000lbs.