We asked Sunoco's Wurth about using aviation fuel in an automobile engine. He was emphatic when he said, "Don't do it. Even though Sunoco is a major producer of aviation fuel, this fuel is specifically blended for aircraft engines. Aircraft operate under very different conditions than automobiles, and the fuel requirements are quite different as well. Aircraft engines generally.... run within a very narrow rpm range. There's no need for transient throttle response in an airplane because after the pilot does the initial engine run-up, the throttle is set in one position and the rpm doesn't normally change until landing. Also, airplanes fly where the air is cold and thin, and the atmospheric pressure is low. These are not even close to the conditions your street machine will see on the ground. Also, since most piston-driven aircraft cruise at 3,000 rpm or so, the burn rate of aviation gas is much too slow for any high performance automotive applications."
I know this references automotive use, but the general idea is that the fuel burn rate is too slow.
I need to find the engineering write up I used to have regarding AvGas in high RPM engines. When I have more time to search.....